3-Iodobenzylzinc bromide
3-Iodobenzylzinc bromide
CAS: 352530-31-5
Molecular Formula: C7H6BrIZn
3-Iodobenzylzinc bromide - Names and Identifiers
| Name | 3-Iodobenzylzinc bromide |
| Synonyms | 3-IodobenzyL 3-Iodobenzylzinc bromide 3-Iodobenzylzinc bromide 0.5 M in Tetrahydrofuran |
| CAS | 352530-31-5 |
3-Iodobenzylzinc bromide - Physico-chemical Properties
| Molecular Formula | C7H6BrIZn |
| Molar Mass | 362.32101 |
| Density | 1.052g/mLat 25°C(lit.) |
| Boling Point | 65°C(lit.) |
| Flash Point | 1°F |
3-Iodobenzylzinc bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R34 - Causes burns |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 1 |
3-Iodobenzylzinc bromide - Introduction
3-Iodobenzylzinc bromide is an organic compound with the chemical formula C7H6BrIZn. It is a white to yellow solid, soluble in organic solvents such as ethanol and dimethylformamide, but insoluble in water.
3-Iodobenzylzinc bromide is mainly used for cross-coupling reactions in organic synthesis reactions, such as Suzuki coupling reactions, Stille coupling reactions, etc. It can be used as an important intermediate in the synthesis of organic compounds, for the synthesis of drugs, pesticides, dyes and coordination reagents.
The method of preparing 3-iodobenzylzinc bromide is generally by reacting zinc bromide with benzyl iodide. First, zinc bromide is reacted with benzyl bromide to produce a benzyl zinc compound. The benzylzinc compound is then reacted with sodium iodide to produce 3-Iodobenzylzinc bromide.
Regarding safety information, 3-Iodobenzylzine bromide may be harmful to humans and the environment, and appropriate safety protection measures should be taken for use and storage. During the operation, personal protective equipment, such as gloves and safety glasses, is required to ensure a well-ventilated experimental environment. At the same time, avoid contact with oxidants and strong acids to prevent fire and explosion.
3-Iodobenzylzinc bromide is mainly used for cross-coupling reactions in organic synthesis reactions, such as Suzuki coupling reactions, Stille coupling reactions, etc. It can be used as an important intermediate in the synthesis of organic compounds, for the synthesis of drugs, pesticides, dyes and coordination reagents.
The method of preparing 3-iodobenzylzinc bromide is generally by reacting zinc bromide with benzyl iodide. First, zinc bromide is reacted with benzyl bromide to produce a benzyl zinc compound. The benzylzinc compound is then reacted with sodium iodide to produce 3-Iodobenzylzinc bromide.
Regarding safety information, 3-Iodobenzylzine bromide may be harmful to humans and the environment, and appropriate safety protection measures should be taken for use and storage. During the operation, personal protective equipment, such as gloves and safety glasses, is required to ensure a well-ventilated experimental environment. At the same time, avoid contact with oxidants and strong acids to prevent fire and explosion.
Last Update：2024-04-09 21:11:58
